This treatment uses polynucleotides (PN), extracted from salmon DNA, to accelerate skin regeneration, repair damaged cells, and boost collagen production for a healthier, more youthful complexion. 

When combined with Microneedling or RF Microneedling, we create precise micro-channels (and with RF, controlled thermal energy) to infuse PN more effectively and amplify collagen remodeling—with minimal downtime.

The Rejuran Salmon DNA Facial is ideal for those who:
Have dry, dull, or aging skin
Want to improve fine lines & wrinkles Need skin healing after sun damage or acne scars
Are looking for a powerful hydration and rejuvenation boost

Polynucleotides stimulate fibroblast activity, enhancing skin repair and collagen synthesis. This helps restore elasticity, strengthen the skin barrier, and improve overall skin quality.

Microneedling improves product delivery and triggers collagen. RF Microneedling adds gentle heat in the dermis for tighter, denser collagen—think repair + remodel in one session.

A topical numbing cream is applied for comfort. Some patients may experience mild redness or tingling, but discomfort is minimal.

For optimal results, we recommend a series of 3-4 treatments, spaced 4 weeks apart.

Mild redness or slight swelling may occur for 1-2 days, but most patients return to normal activities immediately.

Patients often notice improved hydration and glow within weeks, with collagen-building benefits continuing over the next 3 months.

At Honolulu MedSpa, we bring science and luxury together to deliver unmatched skin rejuvenation. Our expert team specializes in regenerative skincare, using state-of-the-art protocols and the latest techniques to maximize the benefits of polynucleotide therapy. We don’t just offer treatments—we provide a deeply personalized approach that targets your unique skin concerns, ensuring faster healing, better hydration, and long-term collagen renewal. With a commitment to excellence and a warm, welcoming experience infused with aloha, we help you achieve radiant, healthy skin that glows from within.